Why is there folic acid in these? people with methylation issues can not use folic acid and are advised to avoid it.

JudNic, We appreciate your question. Methyl Multi without Iron only uses the activated form of folic acid, "folate". This formulation features activated vitamin cofactors and folate as Quatrefolic® (5-MTHF) for optimal utilization. The listing has been updated to reflect this information and help avoid any further confusion. Below is more information on the type of Folate is used in this supplement: "The mechanism of action of Quatrefolic® is related to the action of 5-methyltetrahydrofolate the active part of the proprietary ingredient. 5-methyltetrahydrofolate derives from tetrahydrofolic acid, through a series of metabolic reactions. Tetrahydrofolic acid acts as a coenzyme in several vital metabolic reactions participating in the transfer as acceptors and donors of various one-carbon fragments, involved in the biosynthesis of nucleotides purines and pyrimidines and in the metabolism of several important amino acids. In concert with vitamin B12, folate coenzymes allow the conversion of the amino acid homocysteine to methionine, the lack of this conversion has been associated with various pathologies and diseases. Conversion of tetrahydrofolic acid to 5-methyltetrahydrofolate is mediated by the action of the enzyme methylentetrahydrofolate reductase. In individuals with a genetic defect of methylentetrahydrofolate reductase enzyme conversion is limited, predisposing these individuals for an increased risk for certain disease conditions. Supplementation with 5-methyltetrahydrofolate might be preferable to folic acid, being it is immediately available to react with homocysteine to avoid the possibility of hyperhomocysteineamia." We hope this helps to clarify your concern. Feel free to message us back, or call us (888) 655-4648Pure Therapeutics

Where is this multi made? In United States?

Thanks for your question. Our Methyl Multi without Iron is proudly formulated and produced in the USA in an FDA inspected and GMP certified facility. The ingredients are sourced from the USA, Canada and certain parts of Europe. We do not source any ingredients from China. Please let us know if you have any further questions. Healthy Regards, Pure Therapeutics

Where is this multi made? In United States?

Thanks for your question. Our Methyl Multi without Iron is proudly formulated and produced in the USA in an FDA inspected and GMP certified facility. The ingredients are sourced from the USA, Canada and certain parts of Europe. We do not source any ingredients from China. Please let us know if you have any further questions. Healthy Regards, Pure Therapeutics

ASIN	B00Y3QDOGO
Best Sellers Rank	#3,364 in Health & Household ( See Top 100 in Health & Household ) #49 in Blended Vitamin & Mineral Supplements
Date First Available	May 22, 2015
Is Discontinued By Manufacturer	No
Item model number	8711490050540
Manufacturer	Pure TheraPro Rx
Product Dimensions	3 x 3 x 5 inches; 7.2 ounces

Pure Therapro Rx Methylated Multivitamin for Men and Women | Made in USA | Methyl Multi Without Iron Methyl B12 & Methylfolate | 240 Capsules, 4-Month Supply

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