--- product_id: 45366044 title: "Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed." brand: "nature's trove" price: "β‚±4944" currency: PHP in_stock: true reviews_count: 11 category: "Nature's Trove" url: https://www.desertcart.ph/products/45366044-natures-trove-sam-e-400mg-60-enteric-coated-caplets-vegan store_origin: PH region: Philippines --- # Vegan, Non-GMO, Gluten & Soy free 400mg potent SAM-e dose Enteric coating for max absorption Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. **Brand:** nature's trove **Price:** β‚±4944 **Availability:** βœ… In Stock ## Summary > πŸ’₯ Elevate your wellness game with Nature’s Trove SAM-e β€” where science meets pure, potent care! ## Quick Answers - **What is this?** Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. by nature's trove - **How much does it cost?** β‚±4944 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.ph](https://www.desertcart.ph/products/45366044-natures-trove-sam-e-400mg-60-enteric-coated-caplets-vegan) ## Best For - nature's trove enthusiasts ## Why This Product - Trusted nature's trove brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Pure & Ethical Formula:** Vegan, Kosher, Non-GMO, soy and gluten freeβ€”clean wellness you can trust. - β€’ **Advanced Enteric Coating:** Ensures optimal absorption by protecting active ingredients from stomach acid. - β€’ **Clinically Potent 400mg Dose:** Delivers a powerful, research-backed SAM-e boost for joint and mood support. - β€’ **Freshness Sealed in Blister Packs:** Cold form packaging locks in potency and freshness with every caplet. - β€’ **Trusted Expertise & Proven Results:** Backed by 20+ years of scientific research and a 4.6-star rating from 13,000+ users. ## Overview Nature's Trove SAM-e 400mg caplets offer a premium, vegan-friendly supplement designed for superior absorption and joint health support. Manufactured under GMP standards with a high-purity active isomer, these enteric-coated tablets come in freshness-sealed blister packs. Free from common allergens and artificial additives, this Non-GMO, Kosher-certified formula is trusted by thousands for mood enhancement and pain relief. ## Description PREMIUM QUALITY: Nature's Trove is committed to making the highest quality SAM-e supplements affordable for all consumers. We start with raw material that contains the highest level of the active S.S. Isomer, and manufacture it under strictly controlled GMP conditions. The caplets are enteric coated for optimal absorption, and blister packaged for maximum freshness. Our product is free from allergens, artificial coloring and flavors; suitable for vegan, GMO free, and Kosher certified. EXPERTISE & INDUSTRY LEADERSHIP: Our experts have been working with SAM-e (s-adenosylmethionine) and perfecting its formulation for over 2 decades. We are pleased to present a product that is backed by an incredible amount of science, literature, and research studies. Joint Health & Well-Being: SAM-e may help maintain joint health & well-being. Review: Fast and good source of nutritional supplements. - SAMe, S-adenyl L Methionine has been noted by research to improve cartilage formation. As you see from the name, it is essentially an amino acid. I purchased the 200 and 400 mg quantities. The product is a molecule that is synthesized by some yeasts - bakers' yeast is most common. While I cannot personally double-blind test its effectiveness, scientific evaluation has, and has shown it to increase cartilage recovery. I nearly completely re-tore a long-previously reconstructed knee , and, as my other knee had also been damaged by significant aerial mistakes and landings I sought more than just the usual chondroitin, MSM, etc. Having seen live images of the cartilage damage in my knees, and exploring the research, I strongly feel that SAMe is worth purchase. This brand is naturally-sourced - a good selling point, and it is reasonably priced on comparison to many others. SAMe is also sold as neuroactive, due to its part in the synthesis of serotonin, which was a matter of concern. Serotonin is synthesized through the production and synthesis of this molecule, in great part by mutualist symbiotic enteric microorganisms. Again, because this is natural, it is almost certainly a good nutritional supplement, as enteric organisms tend to change quickly in response to different dietary intake. Thus, it promotes more regular synthesis of one of the most important neurotransmitters. Due to the highly stressful period in which all of us are immersed, I haven't looked deeper into that neurological issue, although we DO know a few things about it. Serotonin itself cannot cross into the brain, and that produced in the intestines affects other physiological processes - we need it. But excess serotonin production in the brain affects males and females differently and the brain's feedback processes tend to act to restore normality (it's possible that some individuals may experience persistent insufficiency OR excess, but those are a small minority. .If you suspect such long-term problem, do consult a medical therapist - Psychologists can refer those with metabolic problems of persistent types to psychiatrists who can test for such problems. But recognize that serotonin understanding is in its infancy, and the past with its SSRIs and other quite invasive drugging, is like using a hammer to fix a computer board or a brain) That, in short, is why I do NOT recommend that people seek neurotropic drugs - from alcohol to other drugs, we interfere with or destroy natural functioning, which it's sometimes better to address ONLY through physical, mental, social activities. SAMe is, though, pretty much methionine, a food, and we may often be deficient in that amino acid - which is why it can improve cartilage formation, as well as other variables like digestion. So, explore the effects of ANYTHING you ingest, and DO NOT just take things because of inane claims unsupported by rigorous scientific research. This company was extremely responsive (FAST!) to my desertcart order, and, so, with its component sourcing, seems a great place from which to purchase nutritional products. While I have experienced reduced pain , I had also been expanding the exercise of joints I injured and reinjured, and so cannot honestly evaluate sensations like pain reduction for others. I use less aspirin since the combination of SAMe, the natural healing process, and slow increase of exercise of affected joints, and as usual recommend any safe reduction of NSAID use. SAMe does not have the deleterious side effects of NSAIDs. Review: Works great for fibromyalgia! - Great price and quality! ## Features - PREMIUM QUALITY: Nature's Trove is committed to making the highest quality SAM-e supplements affordable for all consumers. We start with raw material that contains the highest level of the active S.S. Isomer, and manufacture it under strictly controlled GMP conditions. The caplets are enteric coated for optimal absorption, and blister packaged for maximum freshness. Our product is free from allergens, artificial coloring and flavors; suitable for vegan, GMO free, and Kosher certified. - EXPERTISE & INDUSTRY LEADERSHIP: Our experts have been working with SAM-e (s-adenosylmethionine) and perfecting its formulation for over 2 decades. We are pleased to present a product that is backed by an incredible amount of science, literature, and research studies. - Joint Health & Well-Being: SAM-e may help maintain joint health & well-being. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B071D973TN | | Age Range Description | Adult | | Best Sellers Rank | #3,120 in Health & Household ( See Top 100 in Health & Household ) #35 in Blended Vitamin & Mineral Supplements | | Brand | Nature's Trove | | Brand Name | Nature's Trove | | Container Type | Box | | Customer Reviews | 4.6 out of 5 stars 13,515 Reviews | | Diet Type | Gluten Free | | Dosage Form | Tablets | | Flavor | Unflavored | | Global Trade Identification Number | 00850056289047 | | Item Form | Tablet | | Item Weight | 0.2 Pounds | | Manufacturer | Nature's Trove | | Manufacturer Part Number | TRSAM460 | | Material Features | GMO Free, Gluten Free, Kosher Certified, Vegan | | Number of Items | 1 | | Primary Supplement Type | Non-specific | | Product Benefits | Kosher | | Special Ingredients | Amino Acid | | Specific Uses For Product | Joint pain, Pain Relief | | Total Servings Per Container | 60 | | UPC | 850056289047 | | Unit Count | 60 Count | ## Product Details - **Age Range (Description):** Adult - **Brand:** Nature's Trove - **Diet Type:** Gluten Free - **Flavor:** Unflavored - **Item Form:** Tablet - **Item Weight:** 0.2 Pounds - **Primary Supplement Type:** Non-specific - **Product Benefits:** Kosher - **Special Ingredients:** Amino Acid - **Unit Count:** 60 Count ## Images ![Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - Image 1](https://m.media-amazon.com/images/I/71RRBR4OGpL.jpg) ![Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - Image 2](https://m.media-amazon.com/images/I/813nOuJjT9L.jpg) ![Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - Image 3](https://m.media-amazon.com/images/I/81cYyg8uXNL.jpg) ![Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - Image 4](https://m.media-amazon.com/images/I/81zIYrNYoiL.jpg) ![Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - Image 5](https://m.media-amazon.com/images/I/714En4zgBuL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: What is the net yield of sam-e? 400 or 200mg? if 400mg s-adenosylmethionine tosylate disulfate then it is often a net yield of only 200mg-misleading!!** A: I ordered a bottle of Natures Trove Sam-e 400mg.When it arrived the first thing I noticed on the ingredients labeling was....SAM-E 400mg from 800mg of Sam-e Tosylate Disulfate... Hmmmm. I have always taken NatureMade Sam-e which states only ( Sam-e( S-adenosylmethionine 400mg. and found it excellent and stable. It has very good enteric coating and is consistent as to when I can feel it effecting my mood and energy. I know it is a reliable brand. I am going to give Natures Trove a fair shot as the price is better..... and hope that this difference in labeling of the main ingredient does not mean anything in reference to effectiveness. Does anyone have info to clarify the labeling? **Q: where is this made?** A: Hi, Nature's Trove SAM-e is made in the USA. **Q: Does this really contain titanium dioxide? (says it "might") that's toxic!!!** A: The ingredients are on the box and yes titanium dioxide is listed. Whether it is toxic or not I have no idea. Maybe in the amount that is contained in the product might determine whether it is or not. **Q: The front cover states its a natural deritive of yeast the back of the box says theres no yeast .I called the 1800 number to ask no answere?** A: Hi, SAM-e is derived from a specific natural chemical compound found in yeast however there is no yeast in this product. I hope that answers your question. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Fast and good source of nutritional supplements. *by M***M on July 15, 2020* SAMe, S-adenyl L Methionine has been noted by research to improve cartilage formation. As you see from the name, it is essentially an amino acid. I purchased the 200 and 400 mg quantities. The product is a molecule that is synthesized by some yeasts - bakers' yeast is most common. While I cannot personally double-blind test its effectiveness, scientific evaluation has, and has shown it to increase cartilage recovery. I nearly completely re-tore a long-previously reconstructed knee , and, as my other knee had also been damaged by significant aerial mistakes and landings I sought more than just the usual chondroitin, MSM, etc. Having seen live images of the cartilage damage in my knees, and exploring the research, I strongly feel that SAMe is worth purchase. This brand is naturally-sourced - a good selling point, and it is reasonably priced on comparison to many others. SAMe is also sold as neuroactive, due to its part in the synthesis of serotonin, which was a matter of concern. Serotonin is synthesized through the production and synthesis of this molecule, in great part by mutualist symbiotic enteric microorganisms. Again, because this is natural, it is almost certainly a good nutritional supplement, as enteric organisms tend to change quickly in response to different dietary intake. Thus, it promotes more regular synthesis of one of the most important neurotransmitters. Due to the highly stressful period in which all of us are immersed, I haven't looked deeper into that neurological issue, although we DO know a few things about it. Serotonin itself cannot cross into the brain, and that produced in the intestines affects other physiological processes - we need it. But excess serotonin production in the brain affects males and females differently and the brain's feedback processes tend to act to restore normality (it's possible that some individuals may experience persistent insufficiency OR excess, but those are a small minority. .If you suspect such long-term problem, do consult a medical therapist - Psychologists can refer those with metabolic problems of persistent types to psychiatrists who can test for such problems. But recognize that serotonin understanding is in its infancy, and the past with its SSRIs and other quite invasive drugging, is like using a hammer to fix a computer board or a brain) That, in short, is why I do NOT recommend that people seek neurotropic drugs - from alcohol to other drugs, we interfere with or destroy natural functioning, which it's sometimes better to address ONLY through physical, mental, social activities. SAMe is, though, pretty much methionine, a food, and we may often be deficient in that amino acid - which is why it can improve cartilage formation, as well as other variables like digestion. So, explore the effects of ANYTHING you ingest, and DO NOT just take things because of inane claims unsupported by rigorous scientific research. This company was extremely responsive (FAST!) to my Amazon order, and, so, with its component sourcing, seems a great place from which to purchase nutritional products. While I have experienced reduced pain , I had also been expanding the exercise of joints I injured and reinjured, and so cannot honestly evaluate sensations like pain reduction for others. I use less aspirin since the combination of SAMe, the natural healing process, and slow increase of exercise of affected joints, and as usual recommend any safe reduction of NSAID use. SAMe does not have the deleterious side effects of NSAIDs. ### ⭐⭐⭐⭐⭐ Works great for fibromyalgia! *by E***S on May 15, 2026* Great price and quality! ### ⭐⭐⭐⭐⭐ Good product *by M***R on April 30, 2026* A friend recommended these, they are helping with my anxiety. ## Frequently Bought Together - Nature's Trove SAM-e 400mg 60 Enteric Coated Caplets. Vegan, Kosher, Non-GMO Project Verified, Soy Free, Gluten Free - Cold Form Blister Packed. - L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioactive Forms of Vitamin B9 & B12 (60 Capsules – 60 Servings) - SAM-e 200mg Daily Supplement - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - 60 Enteric Coated Tablets - Cold Form Blister Packed - by Nature’s Trove --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.ph/products/45366044-natures-trove-sam-e-400mg-60-enteric-coated-caplets-vegan](https://www.desertcart.ph/products/45366044-natures-trove-sam-e-400mg-60-enteric-coated-caplets-vegan) --- *Product available on Desertcart Philippines* *Store origin: PH* *Last updated: 2026-05-26*